Tech & Jobs: Microsoft flagged proposed collective redundancies at its Irish units, with at least 60 roles expected to go, mainly tied to Xbox and parts of its commercial business. US-Russia Sanctions: A bipartisan US Senate group says it has a deal with the Trump administration to advance a tougher Russia sanctions bill, aiming to pressure countries that help Moscow’s war economy. Health & Pharma: The US FDA approved PADCEV plus Keytruda (and Keytruda QLEX) for muscle-invasive bladder cancer as neoadjuvant and adjuvant therapy, including for patients not eligible for cisplatin. APEC Business: APEC business leaders in Bangkok backed policy proposals on regional integration, sustainable development, digital innovation and connectivity for submission ahead of November talks. Trade & Industry: Indonesia outlined three export-boost strategies—better use of FTAs, support for MSMEs, and diversification toward South Asia, the Middle East, Africa and Latin America. Finance & Markets: Citi’s tokenized deposit and 24/7 clearing push gained a new customer in Thailand’s Siam Commercial Bank, pointing to interoperability as the next battleground. Energy Connectivity: The EU launched a €5m South Asia energy interconnectivity programme in Nepal to link power markets across the region. Semiconductors: SK hynix listed ADRs on Nasdaq to expand its global AI chip presence. Urban Governance: Singapore’s national development minister said China’s urban governance experience offers lessons as both cities tackle ageing, sustainability and congestion.